About Glycerin Suppositories

Source:

https://www.medicinesforchildren.org.uk/glycerin-glycerol-suppositories-constipation

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An Improved Technique for Preparing Glycerin Suppositories U.S.P.

To improve the firmness and clarity of the product, Dean Tice and Professor Ehrenstein of the Philadelphia College of Pharmacy and Science evolved a new formula and technique based on higher sodium stearate content, higher solution temperature and the use of heated metal molds. Except for a minor modification, this is the formula adopted in U.S.P. XV.

Glycerin (glycerol) suppositories for constipation

Glycerin (glycerol) suppositories for constipation

This leaflet is for parents and carers about how to use this medicine in children. Our information sometimes differs from that provided by the manufacturers, because their information is usually aimed at adults. Please read this leaflet carefully. Keep it somewhere safe so that you can read it again.

Name of medicine

Glycerin (glycerol) suppositories

Why is it important for my child to take this medicine?

When a child is constipated, their stools (poo) are hard and painful to pass. Sometimes a child may try to hold the stool in because of previous pain when going to the toilet . Constipation can also make a child feel quite poorly. Glycerin suppositories are used to stimulate emptying of the bowels and provide rapid relief from constipation.

When should I give glycerin suppositories?

Your doctor will tell you when to use the suppositories.

How much should I give?

Glycerin suppositories are available in 1 g, 2g and 4 g sizes. Your doctor will decide which size (the dose) is right for your child. The dose will be shown on the medicine label.

How should I give glycerin suppositories?

• Wash your hands with soap and hot water.
• Your child should lie on their side or front with, if possible, their knees drawn up towards their chest.
• Hold one buttock gently to one side so that you can see the back passage.
• Unwrap the suppository and hold it with the rounded end close to the back passage.
• Use one finger to push the suppository gently into the back passage. It needs to go in by about 2 cm.
• Wash your hands again with soap and hot water.
• To help make insertion more comfortable you can put a small amount of lubricant (such as K-Y jelly) on the rounded end of the suppository, or moisten it with a little water.
• Lower their legs to a comfortable position to help hold the suppository in place. Your child should stay lying on their side for about 15 minutes to allow the suppository to spread further inside the bowel and to make sure it doesn’t come out.
• If your child feels that the suppository must come out immediately, it may not have been inserted far enough.

When should the medicine start working?

Glycerin suppositories usually work after about 15 minutes. If your child does not empty their bowels (do a poo), do not insert another suppository. Contact your doctor for advice, in case this is because of a problem other than constipation.

What if my child is sick (vomits)?

You do not need to worry if your child is sick, as the suppository will still work.

What if I give too much?

If you are concerned that you may have used too much, contact your doctor or local NHS services (details at end of leaflet). Have the medicine or packaging with you if you telephone for advice.

Are there any possible side-effects?

We use medicines to help our children, but sometimes they have effects that we don’t want (side-effects).

Glycerin suppositories may cause:

• stomach cramps
• irritation around the back passage.

There may sometimes be other side-effects. If you notice anything unusual and are concerned, contact your doctor. You can report any suspected side-effects to a UK safety scheme at www.mhra.gov.uk/yellowcard.

Can other medicines be given at the same time as glycerin suppositories?

• You can give your child medicines that contain paracetamol or ibuprofen, unless your doctor has told you not to.
• Tell your doctor or pharmacist if you have used, or are using, any other medicines to treat your child’s constipation.

Is there anything else I need to know about glycerin suppositories?

• Glycerin suppositories are known as stimulant laxatives. They should only be used to provide rapid relief from temporary constipation. They should not be used to treat chronic (long-term) constipation (unless recommended by your doctor).
• Before giving glycerin suppositories, always increase the amount of high-fibre foods (see below) that your child eats and encourage them to drink plenty of water, or use an ‘osmotic laxative’. This is another type of laxative that works by softening the stools.
• You can help your child’s constipation by giving them high-fibre foods such as fruit, vegetables, bran and high-fibre cereals. Also encourage them to drink plenty of water, which will help to soften the stools. Encourage your child to be active as this will also help their constipation. Your pharmacist, doctor or health visitor will be able to give you advice and support.
• If you think someone else may have used the glycerin suppositories by accident, particularly if they have other health problems, contact your doctor for advice, although they are unlikely to be harmed.

General advice about medicines

• Only give this medicine to your child. Never give it to anyone else, even if their condition appears to be the same, as this could do harm.
• Make sure that you always have enough medicine. Order a new prescription at least 2 weeks before you will run out.
• Make sure that the medicine you have at home has not reached the ‘use by’ date on the packaging. Give old medicines to your pharmacist to dispose of.

Where should I keep this medicine?

• Keep the medicine in a cupboard, away from heat and direct sunlight. It does not need to be kept in the fridge.
• Make sure that children cannot see or reach the medicine.
• Keep the medicine in the container it came in.

Who to contact for more information

Your child’s doctor, pharmacist or nurse will be able to give you more information about glycerin suppositories and about other ways to treat constipation.

Glycerin Pregnancy Warnings

Glycerin has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Glycerin is only recommended for use during pregnancy when benefit outweighs risk.

Glycerin Breastfeeding Warnings

There are no data on the excretion of glycerin into human milk.

How many glycerin suppositories can I take?

Answer:

For best results after using glycerin rectal, stay lying down until you feel the urge to have a bowel movement. This medicine should produce a bowel movement within 15 to 60 minutes after using the suppository. Do not use glycerin rectal more than once in a 24-hour period

Question 3:

What is the formulation of suppositories?

Answer:

Suppositories are a dosage form designed to deliver drugs through rectal and vaginal routes of administration. They evolved as a more convenient alternative form of drug delivery from liquid enema formulations

Question 4:

What happens if you poop after a suppository?

Answer:

Try to avoid passing stool for up to 60 minutes after inserting the suppository, unless it is a laxative. Not passing stool gives the medication enough time to enter the bloodstream and start working

Question 5:

Do glycerin suppositories soften stool?

Answer:

The melting of glycerine suppositories inside the back passage lubricates and softens faecal matter. Lubricating and softening stools helps to prevent straining during a difficult bowel movement. … Glycerine suppositories are very safe to use and do not react with other medication.

Question 6:

Are glycerin suppositories habit forming?

Answer:

If oral laxatives fail, you may be told to try a glycerin suppository half an hour before attempting a bowel movement. … Dulcolax® suppositories stimulate a strong, wave-like movement of rectal muscles, but they are much more habit–forming than glycerin suppositories.

Question 7:

How long should I keep a glycerin suppository in?

Answer:

Adult suppositories are bullet-shaped, while those for children are long and slender. Keep lying down for about 5 minutes. This lets the medicine dissolve. Suppositories should stay in the rectum for 15 to 30 minutes.

Question 8:

Is glycerin suppository safe for babies?

Answer:

If your baby is struggling, it’s been a few days since his or her last bowel movement, and dietary changes haven’t been effective, it might help to place an infant glycerin suppository into your baby’s anus. However, glycerin suppositories are only meant for occasional use.

Question 9:

Do glycerin suppositories expire?

Answer:

Do not use Glycerol Suppositories if you believe you have an intestinal obstruction. Do not use this medicine after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering. If it has expired or is damaged, return it to your pharmacist for disposal.

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